Histological and gene-expression profiles of hi-par hubs. Scatterplots of participation versus neuronal volume density A and partial least squares gene-expression predictor B. C The total number of genes annotated for cognition, learning or memory, and single organism behavior total length of bars , the number of annotated genes predictive of participation dark portion of bars , and the expected number of such genes under the null hypothesis red dashed lines. We used the Allen Institute data on gene expression in adult wild-type mice to estimate the normalized regional expression of 3, genes all genes which were assayed more than once and passed quality control We explored the association between gene-expression profiles and nodal participation by using partial least squares, a versatile technique that combines dimensionality reduction with regression and is well suited for high-dimensional gene-expression data Discussion We have reported an extensive topological and spatial analysis of the tract tracing-based mouse brain connectome. The results showed, in support of our original hypotheses, that the connectome had a complex topology that could not be explained entirely by global minimization of wiring cost. More specifically, high-participation hubs of the connectome mediated many connections between modules, had high axonal wiring costs, slow decay of weight with distance, low neuronal density, high expression of genes enriched for cognitive and behavioral functions, and were not present in cost-minimized network models.
The Rome, Florence Tuscany and The Amalfi Coast
On the observation level, which you can reach via a second elevator ride, see the doodle-on-a-napkin concept that led to the Space Needle design. The designated historic landmark can reach a top speed of 45 miles per hour and weaves between skyscrapers above the city streets. The Frank Gehry-designed building looks like a smashed guitar from above, while inside, its colorful exhibits cover everything from the history of indie video games and horror films to Nirvana, the Seahawks, and more.
At Pacific Science Center , explore galaxies near and far in the planetarium, get up close and personal with colorful creatures in the Tropical Butterfly House, maneuver a two-ton granite ball, find out what it means if you can roll your tongue, and much more. David Newman Chihuly Garden and Glass The Chihuly Garden and Glass museum is dedicated to the work and career of locally born, world-renowned glassblower Dale Chihuly, who was introduced to the craft while studying at the University of Washington.
It is the most comprehensive collection of his art to date, with interior galleries featuring a variety of his work in the medium.
Series 1 consists of records, dating primarily from the s and s, generated by executive officers. These include correspondence and reports of the executive secretary and activities and programs under the direction of that officer, such as branch activities, the business department, and an “expanding program”–a broad term referring to.
Author admin The edition of the Thunderbird Internationals was held on August 1st through the 5th in beautiful Port Townsend, Washington. It was an epic event! Seventeen races over five days! For starters, what better venue for sailing than the historic seaport of Port Townsend? In recent years, the city has become a mecca in the Pacific Northwest for Thunderbirds. There are currently about 14 boats in the local fleet. With a back drop of Mount Baker and the Cascades to the east, the Olympic Mountains to the south, ferries and other boat traffic coming and going, a walkable downtown with lovely shops and restaurants, it was the logical choice to host the 26th Thunderbird International Regatta.
On Monday, the day before the start of the regatta, the race committee went out and held practice races. It was a chance for the Birds to get out and shake off the cobwebs and to check out the competition.
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Shares Pulse first responder to be guest at State of the Union By Associated Press A Florida police officer who was the first on the scene of a deadly nightclub massacre will be a guest at the State of the Union address. Shares 2 men face federal prison sentences for selling opioids By Associated Press Two men in two separate cases will face federal prison sentences after they supplied synthetic opioids to people who later died.
Shares Young widow and children get fresh start By ANDY FILLMORE – Associated Press When Kelsey Still tells you her story of losing and regaining her children and surviving domestic violence, which included cracked ribs in a failed relationship and a tragic end to a difficult marriage, her face shows the pain but her eyes look full of hope. Rick Scott banning state environmental regulators from even using terms such as “global warming,” concerned citizens say they cannot wait for leadership on the climate change issue to come from the top.
Applicants convicted of offences of sexual intercourse without consent & indecent assault in WA. Special leave to granted on He acknowledged telling police earlier that the ‘speed’ belonged to him but said he had done this because he thought he would .
An oceanic climate also called “west coast marine climate” predominates in western Washington, and a much drier semi-arid climate prevails east of the Cascade Range. Major factors determining Washington’s climate include the large semi-permanent high pressure and low pressure systems of the north Pacific Ocean, the continental air masses of North America, and the Olympic and Cascade mountains. In the spring and summer, a high pressure anticyclone system dominates the north Pacific Ocean, causing air to spiral out in a clockwise fashion.
For Washington this means prevailing winds from the northwest bring relatively cool air and a predictably dry season. Dryland farming caused a large dust storm in arid parts of eastern Washington on October 4, This causes Washington’s prevailing winds, the Chinooks , to come from the southwest, bringing relatively warm and moist air masses and a predictably wet season. The term ” Pineapple Express ” is used colloquially to describe the extreme form of the wet-season Chinook winds.
During these events western Washington experienced up to 6 feet 1. In , the Climate Impacts Group at the University of Washington published The Impacts of Climate change in Washington’s Economy, a preliminary assessment on the risks and opportunities presented given the possibility of a rise in global temperatures and their effects on Washington state. Rain shadow Washington experiences extensive variation in rainfall.
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Route description[ edit ] Interstate 5 is the only Interstate to traverse Washington from north to south, serving as the primary highway for the western portion of the state. The stretch of I-5 through Downtown Seattle is the busiest highway in Washington state, with a daily average of over , vehicles in the mainline and express lanes. The bridge is the only point on I-5 where vehicles have to stop for cross traffic, due to the lifts.
I-5 intersects I , the eastern freeway bypass of the Portland metropolitan area , in Salmon Creek near the Vancouver campus of Washington State University.
Church Singles Groups Meet for Fun, Food and Friendship Find new friends in church singles groups all across the country through our growing directory of church singles websites. Make new contacts with people that share your faith and just happen to be single too. While some churches have organized singles groups, others do not.
Basic road map of Portland; click to enlarge Downtown Portland map Portland is an easy city to bike, walk or use public transport. However there are topographical features that affect how streets and roads flow, so planning and maps are important for any journey of more than a few blocks. The verdant West Hills slope up from downtown and divide it from the suburbs of Beaverton, Hillsboro and others.
Much of Portland is a grid, and fairly easy to navigate. Portland is divided into five sectors, sometimes referred to oxymoronically as the “five quadrants”. If you hear Portlanders talking about Southwest or Northeast, they’re probably talking about a sector of the town rather than Arizona or Massachusetts. All Portland addresses contain their designating sector inserted between house number and street name i. The house address numbers increase per block starting from Burnside Street or the Willamette River.
This should make it easier to figure out where things are. The streets of inner Northwest Portland are arranged alphabetically starting with Burnside, followed by Couch, then Davis, etc. Driving around downtown is not recommended: Most people can walk from one end of downtown to the other in 15 min—-faster than driving at times.
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by Peninsula Daily News Bazaars warm up holiday spirit this week North Olympic Peninsula holiday bazaars offer hand-made gifts and Christmas decorations this week.
State of Maryland and Historical Collections Repository: Also included are a broad range of document types from operating records to publications, audio-visual materials, and three-dimensional objects such as toys. In addition the collection contains the personal papers of numerous leaders of the ACEI. Among the many subjects addressed in the collection are early childhood curriculum, teacher education, the history of pre-kindergarten and kindergarten education, and the development of pre-school education in countries other than the United States.
There are also several unprocessed accessions for which preliminary inventories are available. Please contact the curator for more information. Important Information for Users of the Collection Restrictions: This collection is open for research. Please use this identifier to cite or link to this item: Photocopies of original materials may be provided for a fee and at the discretion of the curator.
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What We Do Since the Young Marines’ humble beginnings in with one unit and a handful of boys, the organization has grown to over units with 9, youth and 2, adult volunteers in 46 states, the District of Columbia, Germany, Japan and affiliates in a host of other countries. The Young Marines promotes the mental, moral, and physical development of its members. The program focuses on character building and leadership and promotes a lifestyle that is conducive to being productive members of society.
Who we are NOT The Young Marines program is not a program for youths with serious disciplinary problems, substance abuse issues or lengthy histories in juvenile court. Our Mission The mission of the Young Marines is to positively impact America’s future by providing quality youth development programs for boys and girls that nurtures and develops its members into responsible citizens who enjoy and promote a healthy, drug-free lifestyle..
Membership The Young Marines is open to all youth, boys and girls, ages 8 through completion of high school.
Search the world’s information, including webpages, images, videos and more. Google has many special features to help you find exactly what you’re looking for.
A Mediterranean Climate predominates in western Washington, and a much drier semi-arid climate prevails east of the Cascade Range. Major factors determining Washington’s climate include the large semi-permanent high pressure and low pressure systems of the north Pacific Ocean, the continental air masses of North America, and the Olympic and Cascade mountains. In the spring and summer, a high pressure anticyclone system dominates the north Pacific Ocean, causing air to spiral out in a clockwise fashion.
For Washington, this means prevailing winds from the northwest bring relatively cool air and a predictably dry season. Dryland farming caused a large dust storm in arid parts of eastern Washington on October 4, The air spiraling inward in a counter-clockwise fashion causes Washington’s prevailing winds, the Chinooks , to come from the southwest, and bring relatively warm and moist air masses and a predictably wet season. The term ” Pineapple Express ” is used colloquially to describe the extreme form of the wet-season Chinook winds.
During these events, western Washington experienced up to 6 feet 1. In , the Climate Impacts Group at the University of Washington published The Impacts of Climate change in Washington’s Economy, a preliminary assessment on the risks and opportunities presented given the possibility of a rise in global temperatures and their effects on Washington state.
Thu Jan 29, 3: That’s about double what you should be paying. I’ve been dealing with them since about and have never had a problem with them. Their prices are not always the lowest to be found, but they’re competetive, and I like their service. As for the Archiving question, unless badly damaged to the recording layer , even my oldest Mistui’s still read fine to this day. They’ve held up well, even with the ones I’ve got labels on.
Oct 21, · W Spokane Falls Blvd, Spokane, WA , USA. Get directions. Phone +1 Web Visit website. Make Memorable Moments in Everett and Snohomish County, Washington Back to List 5 Fun Ways to Celebrate the Holiday Season in .
Her black husband was charged. A 16 year old black male has been charged. The suspect is a career criminal. The suspect has been charged with numerous crime. A suspect has been charged with murder. A career criminal has been arrested. A black male, who is a career criminal, has been charged. A black male has been charged with his murder and the attempted murder of his mother.
A black male has been charged with the murder. They also wounded three other white victims. Suspects have been charged. Police are seeking two black males. The same perps also attacked others. A black father and son have been arrested for the murder.
Interstate 5 in Washington
Patents searched by Lindquist’s Patent Attorney for reference purposes in applying for his first U. Patent – August September 18 4. Edberg, and Engineer Tom Jacob. McMillin – November 11 6. This basic concept eventually led to a more complex U.
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Drug Rehabilitation Facility In Richmond Estimate prevalence of cognitive problems due to hypoxic brain injury in out-of-hospital arrest OHCA survivors referred for and association with quality of life as well as autonomy and participation. Cognitive problems were defined if MMSE Emerging evidence indicates mobile technology-based strategies may improve access to secondary prevention and reduce risk factors in patients.
However, little is known about patients’ use of mobile technology, particularly for health reasons and whether the usage varies across patient demographics. This study aimed to describe patients’ use of mobile technology and to determine variations between age groups after adjusting for education, employment, and confidence with using mobile technology.
Participants completed a survey on the use of mobile technology devices, features used, confidence with using mobile technology, willingness and interest in learning, and health-related use. The most common diagnoses were percutaneous coronary intervention Technology was used by